Endocrine Abstracts

Background: Hyponatraemia is the most common electrolyte abnormality, encountered in up to 30% of inpatients. Plasma sodium levels <125 mmol/l are classed as severe and can be associated with drowsiness, confusion, ataxia and personality change. In mild hyponatraemia, the patient is usually asymptomatic, although studies have shown chronic low sodium of any level may be associated with increased mortality and longer hospital stays. Vasopressin receptor antagonist (tolvapta...